Solitary neurofibroma in the abdominal wall of a patient without neurofibromatosis: case report
Keywords:
neurofibroma, nerve sheath neoplasm, case reports, abdominal wall, neurofibromatoses, fibroblasts
Abstract
Introduction. Solitary neurofibromas are benign tumors, often the manifestation of neurofibromatosis, and reflect a hereditary pathology with several variants. The clinicalmanifestations of solitary neurofibromas change according to their location and can generate a variety of symptoms. Usually, solitary neurofibromas are located in the skin and rarely in other places. Surgical removal is the only treatment; malignant transformation and recurrence are unusual.
Objective. A case is reported of solitary neurofibroma in the abdominal wall of a 19-year-old patient without neurofibromatosis.
Materials and methods. Articles included are from Proquest, Pubmed and Ovid databases. Key words used were neurofibroma, tumors of the neural sheath, and case report. The search is current as of May 24, 2007.
Conclusions. This case appears to be the first one with these characteristics reported in the English and Spanish medical literature.
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References
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2. Sinha R, Paul R, Sen I, Sikdar B. A solitary huge neurofibroma of the soft palate. J Laryngol Otol. 2002;116:637-8.
3. Rha S, Byun J, Jung S, Chun J, Lee H, Lee J. Neurogenic tumors in the abdomen: tumor types and imaging characteristics. RadioGraphics. 2003;23:29-43.
4. Shaida A, Yung M. Neurofibroma of the pinna. Ear Nose Throat J. 2007;86:36-8.
5. Kostakopoulos A, Chorti M, Protogerou V, Kokkinou S. Solitary neurofibroma of kidney: clinical, histological and chromosomal appeareance. Int Urol Nephrol. 2003;35:11-3.
6. Venadero F, Rodríguez M, Merelo V, Cervantes A, Ramos A. Neurofibroma solitario. Comunicación de dos casos. Rev Cent Dermatol Pascua. 2004;13:99-102.
7. Panteris V, Vassilakaki T, Vaitsis N, Elemenoglou I, Mylonakou I, Karamanolis D. Solitary colonic neurofibroma in a patient with transient segmental colitis: case report. World J Gastroenterol. 2005;11:5573-6
8. Kilmurray L, Ortega L, Martínez A, Sanz J. Neurofibroma with psammoma bodies. Histol Histopathol. 2006;21:965-8.
9. Viskochil D. It takes two to tango: mast cell and Schwann cell interactions in neurofibromas. J Clin Invest. 2003;112:1791-3.
10. Li F, Cheng J, He S, Li N, Zhang M, Zhang X, et al. Primary neurofibroma of the common bile duct as an unusual cause of obstructive jaundice: A case report. Dig Dis Sci. 2005;50:1166-8.
11. Deliveliotis C, Albanis S, Skolarikos A, Varkaraki J. Solitary neurofibroma of the spermatic cord. Int Urol Nephrol. 2002;34:373-5
12. Chang C, Provost D, LeVoyer T, Ellison R. Abdominal wall neurofibroma presenting as an inguinal hernia. Mil Med. 2004;169:192-3.
13. Surwald C, Salam M, Rowe R. A solitary neurofibroma of the palatine tonsil. J Laryngol Otol. 2002;116: 1050-2.
14. Tanaka H, Patel U, Coniglio J, Rubio A. Solitary subglottic neurofibroma: MR Findings. AJNR Am J Neuroradiol. 1997;18:1726-8
15. Amor-Dorado J, Candia J, Costa C, Mate A, Rossi J. Neurofibroma cervical solitario. ORL-DIPS. 2002;29:192-5.
16. Sharma V, Newton G. Cervical intramedullary neurofibroma. J Korean Med Sci. 1990;5:165-7.
17. Watanuki F, Ohwada S, Hosomura Y, Okamura S, Kawashima Y, Tanahashi Y, et al. Small ileal neurofibroma causing intussusception in a non-neurofibromatosis patient. J Gastroenterol. 1995;30:113-6.
18. Abramson L, Orkin B, Schwartz A. Isolated colonic neurofibroma manifested by massive lower gastrointestinal bleeding and intussusception. South Med J. 1997;90:952-4.
19. Frick E Jr, Lapos L, Vargas H. Solitary neurofibroma of the anal canal: report of two cases. Dis Colon Rectum. 2000;43:109-12.
20. Turkyilmaz Z, Sonmez K, Karabulut R, Dursun A, Isik I, Basaklar C, et al. A childhood case of intrascrotal neurofibroma with a brief review of the literature. J Pediatr Surg. 2004;39:1261-3.
21. Issa MM, Yagol R, Tsang D. Intrascrotal neurofibromas. Urology. 1993;41:350-2.
22. Venter P, Rohm G, Slabber C. Giant neurofibromas of the labia. Obstet Gynecol. 1981;57:128-30.
2. Sinha R, Paul R, Sen I, Sikdar B. A solitary huge neurofibroma of the soft palate. J Laryngol Otol. 2002;116:637-8.
3. Rha S, Byun J, Jung S, Chun J, Lee H, Lee J. Neurogenic tumors in the abdomen: tumor types and imaging characteristics. RadioGraphics. 2003;23:29-43.
4. Shaida A, Yung M. Neurofibroma of the pinna. Ear Nose Throat J. 2007;86:36-8.
5. Kostakopoulos A, Chorti M, Protogerou V, Kokkinou S. Solitary neurofibroma of kidney: clinical, histological and chromosomal appeareance. Int Urol Nephrol. 2003;35:11-3.
6. Venadero F, Rodríguez M, Merelo V, Cervantes A, Ramos A. Neurofibroma solitario. Comunicación de dos casos. Rev Cent Dermatol Pascua. 2004;13:99-102.
7. Panteris V, Vassilakaki T, Vaitsis N, Elemenoglou I, Mylonakou I, Karamanolis D. Solitary colonic neurofibroma in a patient with transient segmental colitis: case report. World J Gastroenterol. 2005;11:5573-6
8. Kilmurray L, Ortega L, Martínez A, Sanz J. Neurofibroma with psammoma bodies. Histol Histopathol. 2006;21:965-8.
9. Viskochil D. It takes two to tango: mast cell and Schwann cell interactions in neurofibromas. J Clin Invest. 2003;112:1791-3.
10. Li F, Cheng J, He S, Li N, Zhang M, Zhang X, et al. Primary neurofibroma of the common bile duct as an unusual cause of obstructive jaundice: A case report. Dig Dis Sci. 2005;50:1166-8.
11. Deliveliotis C, Albanis S, Skolarikos A, Varkaraki J. Solitary neurofibroma of the spermatic cord. Int Urol Nephrol. 2002;34:373-5
12. Chang C, Provost D, LeVoyer T, Ellison R. Abdominal wall neurofibroma presenting as an inguinal hernia. Mil Med. 2004;169:192-3.
13. Surwald C, Salam M, Rowe R. A solitary neurofibroma of the palatine tonsil. J Laryngol Otol. 2002;116: 1050-2.
14. Tanaka H, Patel U, Coniglio J, Rubio A. Solitary subglottic neurofibroma: MR Findings. AJNR Am J Neuroradiol. 1997;18:1726-8
15. Amor-Dorado J, Candia J, Costa C, Mate A, Rossi J. Neurofibroma cervical solitario. ORL-DIPS. 2002;29:192-5.
16. Sharma V, Newton G. Cervical intramedullary neurofibroma. J Korean Med Sci. 1990;5:165-7.
17. Watanuki F, Ohwada S, Hosomura Y, Okamura S, Kawashima Y, Tanahashi Y, et al. Small ileal neurofibroma causing intussusception in a non-neurofibromatosis patient. J Gastroenterol. 1995;30:113-6.
18. Abramson L, Orkin B, Schwartz A. Isolated colonic neurofibroma manifested by massive lower gastrointestinal bleeding and intussusception. South Med J. 1997;90:952-4.
19. Frick E Jr, Lapos L, Vargas H. Solitary neurofibroma of the anal canal: report of two cases. Dis Colon Rectum. 2000;43:109-12.
20. Turkyilmaz Z, Sonmez K, Karabulut R, Dursun A, Isik I, Basaklar C, et al. A childhood case of intrascrotal neurofibroma with a brief review of the literature. J Pediatr Surg. 2004;39:1261-3.
21. Issa MM, Yagol R, Tsang D. Intrascrotal neurofibromas. Urology. 1993;41:350-2.
22. Venter P, Rohm G, Slabber C. Giant neurofibromas of the labia. Obstet Gynecol. 1981;57:128-30.
How to Cite
1.
Barajas JS, Flórez Salamanca L. Solitary neurofibroma in the abdominal wall of a patient without neurofibromatosis: case report. Biomed. [Internet]. 2009 Dec. 1 [cited 2025 Apr. 4];29(4):501-5. Available from: https://revistabiomedicaorg.biteca.online/index.php/biomedica/article/view/123
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Published
2009-12-01
Issue
Section
Case presentation
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