Bone involvement in non-congenital syphilis
Abstract
We documented two stages of bone involvement due to syphilis in two adult patients infected with human immunodeficiency virus. Bony lesions of secondary versus tertiary syphilis cannot be differentiated on clinical or radiologic grounds alone. Given the rarity of this clinical presentation, there is no consensus on treatment duration and related outcomes.
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References
Miller TT. Bone tumors and tumorlike conditions: analysis with conventional radiography. Radiol. 2008;246:662-74. https://doi.org/10.1148/radiol.2463061038
Restrepo CS, Lemos DF, Gordillo H, Odero R, Varghese T, Tiemann W, et al. Imaging findings in musculoskeletal complications of AIDS. RadioGraphics. 2004;24:1029-49. https://doi.org/10.1148/rg.244035151
Peterman TA, Su J, Bernstein KT, Weinstock H. Syphilis in the United States: on the rise? Expert Rev Anti Infect Ther. 2015;13:161-8. https://doi.org/10.1586/14787210.2015.990384
Golden MR, Marra CM, Holmes KK. Update on syphilis: Resurgence of an old problem. JAMA. 2003;290:1510. https://doi.org/10.1001/jama.290.11.1510
Lynn W, Lightman S. Syphilis and HIV: A dangerous combination. Lancet Infect Dis. 2004;4:456-66. https://doi.org/10.1016/S1473-3099(04)01061-8
Reynolds FW, Wasserman H. Destructive osseous lesions in early syphilis. Arch Intern Med. 1942;69:263. https://doi.org/10.1001/archinte.1942.00200140101008
Thompson RG, Preston RH. Lesions of the skull in secondary syphilis. Am J Syph Gonorrhea Vener Dis. 1952;36:332-41.
Ehrlich R, Kricun M. Radiographic findings in early acquired syphilis: Case report and critical review. Am J Roentgenol. 1976;127:789-92. https://doi.org/10.2214/ajr.127.5.789
King AJ, Catterall RD. Syphilis of bones. Sex Transm Infect. 1959;35:116-28.
Kandelaki G, Kapila R, Fernandes H. Destructive osteomyelitis associated with early secondary syphilis in an HIV-positive patient diagnosed by Treponema pallidum DNA polymerase chain reaction. AIDS Patient Care STDS. 2007;21:229-33. https://doi.org/10.1089/apc.2006.0084
Park K-H, Lee MS, Hong IK, Sung J-Y, Choi S-H, Park SO, et al. Bone involvement in secondary syphilis: A case report and systematic review of the literature. Sex Transm Dis. 2014;41:532-7. https://doi.org/10.1097/OLQ.0000000000000164
Workowski KA, Bolan GA, Centers for Disease Control and Prevention. Sexually transmitted diseases treatment guidelines, 2015. MMWR Recomm Rep. 2015;64:1-137.
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