Amyloidosis in infected Didelphis marsupialis.

Diana Milena Roa, Ladys Sarmiento, Gerzaín Rodríguez, .

DOI: https://doi.org/10.7705/biomedica.v22i3.1160
Keywords: didelphis marsupialis, visceral leishmaniasis, secondary amyloidosis
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Abstract

A male opossum, Didelphis marsupialis, captured in Teruel (Huila), Colombia, was inoculated intraperitoneally with 1 x 10(6) promastigotes of Leishmania chagasi (MHOM/CO/84/CL044B). The animal died 5 weeks after inoculation. Autopsy revealed signs of visceral leishmaniasis along with amastigote parasite form in Kupffer cells and spleen macrophages. Amyloid deposits in liver and spleen were demonstrated by histological staining and electron microscopy. The rapid death was considered a consequence of a secondary, reactive amyloidosis.

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  • Diana Milena Roa Laboratorio de Patología, Instituto Nacional de Salud, Bogotá, D.C.
  • Ladys Sarmiento Unidad de Microscopía y Análisis de Imágenes, Instituto Nacional de Salud, Bogotá, D.C.
  • Gerzaín Rodríguez Laboratorio de Patología, Instituto Nacional de Salud, Bogotá, D.C. Departamento de Patología, Facultad de Medicina, Universidad Nacional de Colombia, Bogotá, D.C.
How to Cite
1.
Roa DM, Sarmiento L, Rodríguez G. Amyloidosis in infected Didelphis marsupialis. Biomed. [Internet]. 2002 Sep. 1 [cited 2026 Mar. 10];22(3):237-40. Available from: https://revistabiomedicaorg.biteca.online/index.php/biomedica/article/view/1160
Published
2002-09-01
Issue
Vol. 22 No. 3 (2002)
Section
Imágenes en biomedicina

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