Onychomadesis secondary to mouth, hand and foot disease: Case report

Abstract

A previously healthy 5-year-old girl presented with Hand, Foot, and Mouth Disease (HFMD) and, one month later, developed onychomadesis, with detachment of the nail plates on both fingers and toes, which resolved spontaneously.
After HFMD, she exhibited nail bed elevation at the proximal region of the nails on the second and third fingers of both hands. This elevation was painless, without bleeding, and later involved all toes.
The condition resolved spontaneously over the following three months, with new, healthy nail growth.
Onychomadesis is a rare complication of HFMD in our region and is associated with atypical forms of the disease, indicating a variation in the host response to common infections with Coxsackie viruses. Reporting such cases is essential to understand these benign and self-limited variations, prevent misdiagnoses, and appropriately inform parents.