Association among hepatoma, cirrosis and hepatitis B incidence in Cali

Abstract

The purpose of the study was to measure cirrhosis. hepatoma and hepatitis B incidences in Cali, Colombia, and compare them according to geographical area, local health systems (SILOS) and neighborhoods. The coefficients r were high and statistically significant according to SILOS, as follows: CHC-CIRROSIS, r.0.82; IC: 0.03-0.98 and Pc0.05; HB-CIRROSIS, r=0.89; IC: 0.3-0.99 and Pc0.05; HB-CHC, r=0.9; IC: 0.03-0.99 and P<0.05. With respect to neighborhoods, the coefficient r was high and significant between CHC and cirrhosis, r=0.65; IC: 0.29-0.85 and Pc0.05, while r were low and not statiscally significant between hepatitis E and the other two diseases: HE-CIRROSIS, r=0.22; IC: 0.02-0.61; HB-CHC, r=0.42: IC: 0.03-0.73 and P>0.05. These results suggest an association among the events described for the three diseases and allow us to priorize the geographic areas for promotion and prevention programs. The cost-effectivity study in the five neighborhoods with the highest risk, based on New York City's suveillance and vaccination program, 987-1988, showed that immunization is seventy five times better than treatment of liver cronic diseases.