Genómica en parasitología: avances y desafíos

Ramírez C, Dea-Ayuela MA, Gutiérrez-Blásquez MD, Bolas-Fernández F, Requena JM, Puerta CJ. Identification of HSP70-RNA messenger interacting proteins in Leishmania braziliensis. J Proteomics. 2013;94:124-37. https://doi.org/10.1016/j.jprot.2013.09.008

Nocua PA, Ramírez CA, Requena JM, Puerta CJ. Leishmania braziliensis SCD6 and RBP42 proteins, two factors with RNA binding capacity. Parasit Vectors. 2017;10:e610. https://doi.org/10.1186/s13071-017-2557-y

Nocua PA, Requena JM, Puerta CJ. Identification of the interactomes associated with SCD6 and RBP42 proteins in Leishmania braziliensis. J Proteomics. 2021;233:e104066. https://doi.org/10.1016/j.jprot.2020.104066

Ramírez JC, Cura CI, da Cruz Moreira O, Lages-Silva E, Juiz N, Velázquez E, et al. Analytical validation of quantitative real-time PCR methods for quantification of Trypanosoma cruzi DNA in blood samples from Chagas disease patients. J Mol Diagnostics. 2015;17:605- 15. https://doi.org/10.1016/j.jmoldx.2015.04.010

Besuschio S, Llano M, Benatar AF, Monerat S, Cruz I, Picardo A, et al. Analytical sensitivity and specificity of a loop-mediated isothermal amplification (LAMP) kit prototype for detection of Trypanosoma cruzi DNA in human blood samples. PLoS Negl Trop Dis. 2017;11:e0005779. https://doi.org/10.1371/journal.pntd.0005779

Swapna LS, Parkinson J. Genomics of apicomplexan parasites. Crit Rev Biochem Mol Biol. 2017;52:254-73. https://doi.org/10.1080/10409238.2017.1290043

Sabalette KB, Campo VA, Sotelo-Silveira JR, Smircich P, De Gaudenzi JG. Transcriptomic analysis of N-terminal mutated Trypanosoma cruzi UBP1 knockdown underlines the importance of this RNA-binding protein in parasite development. PLoS Negl Trop Dis. 2024;18:e0012179. https://doi.org/10.1371/journal.pntd.0012179

Pandit K, Surolia N, Bhattacharjee S, Karmodiya K. The many paths to artemisinin resistance in Plasmodium falciparum. Trends Parasitol. 2023;39:1060-73. https://doi.org/10.1016/j.pt.2023.09.011

Pardo-Rodríguez D, Lasso P, Santamaría-Torres M, Cala MP, Puerta CJ, Méndez JJ, et al. Clethra fimbriata hexanic extract triggers alteration in the energy metabolism in epimastigotes of Trypanosoma cruzi. Front Mol Biosci. 2023;10:e1206074. https://doi.org/10.3389/fmolb.2023.1206074

Kratz JM, Gonçalves KR, Romera LM, Moraes CB, Bittencourt-Cunha P, Schenkman S, et al. The translational challenge in Chagas disease drug development. Mem Inst Oswaldo Cruz. 2022;117:e200501. https://doi.org/10.1590/0074-02760200501

Ruiz E, Ramírez CA, Nocua PA, Requena JM, Puerta CJ. Identificación de proteínas reguladoras de la expresión génica en tripanosomátidos. Rev Acad Colomb Cienc Ex Fis Nat. 2018;42:306-18. https://doi.org/10.18257/raccefyn.671

Michel-Todó L, Reche PA, Bigey P, Pinazo MJ, Gascón J, Alonso-Padilla J. In silico design of an epitope-based vaccine ensemble for Chagas disease. Front Immunol. 2019;10:e2698. https://doi.org/10.3389/fimmu.2019.02698

Puerta CJ, Cuéllar A, Lasso P, Mateus J, González JM. Trypanosoma cruzi-specific CD8+ T cells and other immunological hallmarks in chronic Chagas cardiomyopathy: Two decades of research. Front Cell Infect Microbiol. 2023;12:1075717. https://doi.org/10.3389/fcimb.2022.1075717

Ros-Lucas A, Gabaldón-Figueira JC, Martínez-Peinado N, Losada-Galván I, Posada E, Escabia E, et al. Transcriptomic evidence of immune modulation in subjects with chronic Trypanosoma cruzi infection. J Infect Dis. 2024;28:jiae429. https://doi.org/10.1093/infdis/jiae429

Lecoeur H, Prina E, Gutiérrez-Sánchez M, Späth GF. Going ballistic: Leishmania nuclear subversion of host cell plasticity. Trends Parasitol. 2022;38:205-16. https://doi.org/10.1016/j.pt.2021.09.009

Ruiz-Márvez E, Ramírez CA, Requena JM, Puerta CJ. A dataset of proteins associated with Trypanosoma cruzi LYT1 mRNAs. Data Brief. 2022;41:e107953. https://doi.org/10.1016/j.dib.2022.107953